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A new reagent for the preparation of glycoconjugates
1Max-Planck-Institut für Biochemie, Abteilung Peptidchemie, Martinsried bei München.
Abstract:
The thioglycoside derivative 2-carbazoylethyl 1-thio-beta-D-galactopyranoside hydrochloride was synthesized. Conversion of the carbazoyl group into the reactive azidocarbonyl function leads to a well suited reagent for the preparation of glycoconjugates via amidation of proteins or synthetic carriers in aqueous media.