Related Experiment Video
Updated: Jan 4, 2026

09:34
Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
Published on: April 4, 2018
34.5K
The PATRIC Bioinformatics Resource Center: expanding data and analysis capabilities.
James J Davis1,2, Alice R Wattam2,3, Ramy K Aziz4,5
1University of Chicago Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL 60637, USA.
Nucleic Acids Research
|November 1, 2019
Summary
The PathoSystems Resource Integration Center (PATRIC) now offers enhanced bioinformatics tools for bacterial pathogens. Updates include new web-based comparative analyses and a command-line interface for easier data access and analysis.
Area of Science:
- Bioinformatics
- Genomics
- Microbial Pathogenesis
Background:
- The PathoSystems Resource Integration Center (PATRIC) is a key bioinformatics resource for bacterial research.
- PATRIC provides access to over 250,000 bacterial genomes with curated metadata.
- There is a growing demand for accessible bioinformatics tools due to the rise in omics research.
Purpose of the Study:
- To report recent updates and improvements to the PATRIC resource.
- To enhance the utility of PATRIC for analyzing bacterial pathogens and other bacteria.
- To support the increasing need for user-friendly bioinformatics services.
Main Methods:
- Development of new web-based comparative analysis tools.
- Introduction of eight new streamlined bioinformatics services.
- Release of a command-line interface for bulk data analysis and querying.
Main Results:
- PATRIC now offers expanded web-based visualization and comparative analysis capabilities.
- Eight new services have been integrated to simplify complex bioinformatic workflows.
- A command-line interface is now available for efficient data access and analysis.
Conclusions:
- The recent updates significantly enhance PATRIC's capabilities for bacterial genomics and bioinformatics.
- These improvements aim to meet the growing demand for accessible and powerful omics analysis tools.
- PATRIC continues to be a valuable resource for researchers studying bacterial pathogens.

