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Updated: Jan 4, 2026

Tools for the Real-Time Assessment of a Pseudomonas aeruginosa Infection Model
Published on: April 6, 2021
Putting an end to the Pseudomonas aeruginosa IQS controversy
1Department of Bioengineering Sciences, Laboratory of Microbiology, Vrije Universiteit Brussel, Brussels, Belgium.
Abstract:
Despite published evidence that IQS (2-(2-hydroxylphenyl)-thiazole-4-carbaldehyde) is in fact aeruginaldehyde, a by-product of the siderophore pyochelin biosynthesis or degradation and that the ambABCDE genes are not responsible for IQS synthesis, several authors, including in top review journals, perpetuate the wrong information. I hope that this short comment will clarify the situation once and for all.
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