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[Simulation of industrial fermentation: current status and future perspectives].
Demao Li1, Wuxi Chen1, Wei Guo1
1Tianjin Key Laboratory for Industrial Biosystems and Bioprocessing Engineering, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China.
Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology
|November 1, 2019
Summary
Mathematical simulation enhances understanding of industrial fermentation and microbial systems. This approach aids in designing new synthetic organisms and optimizing large-scale biotechnological production processes.
Area of Science:
- Biotechnology
- Bioprocess Engineering
- Microbial Systems
Background:
- Industrial fermentation is a cornerstone of industrial biotechnology for large-scale production.
- Mathematical simulation offers a powerful tool to understand complex microbial behaviors and fermentation dynamics.
- Accurate modeling is crucial for advancing synthetic biology and bioprocess optimization.
Purpose of the Study:
- To provide an in-depth overview of industrial fermentation systems.
- To explore the evolution and application of mathematical simulation in this field.
- To classify and analyze mathematical models used in fermentation processes.
Main Methods:
- Review and synthesis of existing literature on industrial fermentation.
- Analysis of the characteristics and development of mathematical simulation techniques.
- Classification and functional description of various mathematical models.
Main Results:
- Detailed description of industrial fermentation system characteristics.
- Comprehensive review of the development and classification of mathematical models.
- Exploration of the potential for whole fermentation system simulation.
Conclusions:
- Mathematical simulation is vital for deepening the understanding of microorganisms and fermentation.
- Modeling provides solutions for constructing novel synthetic organisms.
- Future trends point towards integrated simulation of entire fermentation systems.
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