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The significance of 3H-thymidine degradation in cell culture experiments with special reference to rheumatoid

P J Nykänen1, P V Raunio, P U Kankaanpää

  • 1Fourth Department of Medicine, Helsinki University Central Hospital, Finland.

APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica
|September 1, 1988
PubMed

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When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
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