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Management Options for Premature Ejaculation and Delayed Ejaculation in Men.

Patrick Martin-Tuite1, Alan W Shindel1

  • 1Department of Urology, University of California, San Francisco, CA, USA.

Sexual Medicine Reviews
|November 1, 2019
PubMed
Summary
This summary is machine-generated.

Premature ejaculation (PE) and delayed ejaculation (DE) affect many men, with treatments like psychotherapy and medications showing some efficacy. However, no treatments are FDA-approved, highlighting the need for novel therapies for these common sexual health concerns.

Keywords:
AnorgasmiaDelayed EjaculationPharmacotherapy of Delayed EjaculationPharmacotherapy of Premature EjaculationPremature EjaculationSexual Dysfunction

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Area of Science:

  • Sexual Medicine
  • Men's Health
  • Urology

Background:

  • Premature ejaculation (PE) and delayed ejaculation (DE) are prevalent conditions affecting male sexual health.
  • These ejaculatory disorders are often poorly understood and pose management challenges for specialists.

Purpose of the Study:

  • To review and summarize current medical management strategies for PE and DE in men.
  • To critically analyze the evidence base for various treatment options.

Main Methods:

  • A comprehensive literature review was performed using PubMed and clinicaltrials.gov.
  • The review focused on double-blind, placebo-controlled trials and meta-analyses published up to May 2019.
  • Peer-reviewed studies on treatment efficacy and methodological rigor were analyzed.

Main Results:

  • For PE, psychotherapy, pharmacotherapy (SSRIs, local anesthetics), and procedural interventions show efficacy, though often off-label.
  • Education and mental health assessments are crucial for PE management.
  • For DE, limited evidence supports psychotherapy, pharmacotherapy, and penile vibratory stimulation.

Conclusions:

  • Current management options for PE and DE lack formal FDA approval.
  • There is a significant need for the development of new and effective treatments for ejaculatory disorders.