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Highly Combinatorial Genetic Interaction Analysis Reveals a Multi-Drug Transporter Influence Network

Albi Celaj1, Marinella Gebbia2, Louai Musa2

  • 1Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON M5G 1X5, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Computer Science, University of Toronto, Toronto, ON M5T 3A1, Canada.

Cell Systems
|November 1, 2019
PubMed

Keywords:
ABC transporterscombinatorial genetic analysisdrug effluxdrug resistanceepistasisgenetic modelinggenotype-to-phenotype modelinghigh-order genetic interactionsinterpretable neural networkvisible neural network

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