A relationship-based approach to improving clinical trials: The imCORE research network experience

Area of Science:

• Oncology
• Immunotherapy
• Clinical Trial Operations

Background:

• Cancer immunotherapy research is rapidly evolving, increasing demand for new therapies.
• Leading cancer institutions face growing demands for research.
• Roche established the immunotherapy Centers of Research Excellence (imCORE) Network to foster collaboration.

Purpose of the Study:

• To introduce the rationale, design, and success factors of Roche-sponsored clinical trials within the imCORE Network.
• To highlight improvements in clinical trial operations between sponsors and trial sites.
• To share experiences for broader research community advancement.

Main Methods:

• Focus on operational excellence in Roche-sponsored trials within the imCORE Network.
• Analysis of critical components and success factors for sponsored trials.
• Examination of relationship architecture, communication, and information sharing.

Main Results:

• Successful implementation of sponsored trials through effective collaboration.
• Tangible improvements in clinical trial operations achieved.
• Overcoming historical inefficiencies via new processes and tools.

Conclusions:

• The imCORE Network's operational excellence pillar is effective due to stakeholder dedication.
• Sustainable worldwide research collaboration drives innovation in cancer therapy.
• Sharing these operational experiences advances collective patient care.