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Smoking, gastric secretion and inhibition by cimetidine
M Deakin1, J K Ramage, J G Williams
1Department of Gastroenterology, Royal Naval Hospital, Haslar, Gosport, England.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
|January 1, 1988
Abstract:
The pharmacologic response to cimetidine was studied in 8 patients with duodenal ulcers in remission whilst smoking and during abstinence. No significant difference was found in overnight intra-gastric acidity, acid or pepsin output. These data do not support the hypothesis that pharmacologic response to H2 receptor antagonists is impaired in smokers.