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Variations in tuberculosis prevalence, Russian Federation: a multivariate approach
Ivan Meshkov1, Tatyana Petrenko1, Olivia Keiser2
1FSBI Novosibirsk Tuberculosis Research Institute, Ministry of Health of the Russian Federation, Novosibirsk, Okhotskaya street 81A, 630040, Russian Federation.
Bulletin of the World Health Organization
|November 2, 2019
Summary
Tuberculosis trends in Russia show regional variations, with some areas needing urgent intervention. Improving tuberculosis services can help control the disease effectively.
Area of Science:
- Epidemiology
- Public Health
- Infectious Disease Control
Background:
- Siberian and Far Eastern federal districts have the highest tuberculosis burden in Russia.
- Understanding epidemiological trends is crucial for targeted interventions.
Purpose of the Study:
- To analyze tuberculosis epidemiological trends in high-burden Russian federal districts.
- To identify regions requiring priority interventions.
Main Methods:
- Principal coordinate analysis applied to 68 variables (2003-2016).
- Data from 21 regions covering 25.5 million people.
- Identification and ranking of regions based on tuberculosis profiles.
Main Results:
- Tuberculosis notifications decreased from 123.3 to 82.3 per 100,000 population (2003-2016).
- Three key indicators explained 55% of variation: prevalence/notifications, disease severity, and multidrug-resistance.
- Chukotka, Jewish Autonomous Oblast, and Tyva Republic identified as high-priority intervention areas.
Conclusions:
- Regional variations in tuberculosis epidemiology likely stem from differing service quality.
- Principal coordinate analysis enables precise, focused tuberculosis control efforts.
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