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Adolescent rat social play: Amygdalar proteomic and transcriptomic data.
Navatha Alugubelly1,2, Afzaal N Mohammed1,2, Mariola J Edelmann3
1Center for Environmental Health Sciences, USA.
Data in Brief
|November 2, 2019
Summary
This study presents proteomic and transcriptomic data from adolescent rat amygdala after social play. It reveals molecular changes in the brain associated with social behavior in young rats.
Area of Science:
- Neuroscience
- Molecular Biology
- Proteomics
- Transcriptomics
Background:
- Social play is crucial for adolescent development.
- The amygdala plays a key role in social behavior.
- Understanding molecular changes during social play is important.
Purpose of the Study:
- To provide proteomic and transcriptomic data of the rat amygdala following social play.
- To compare gene and protein expression in behaviorally active vs. inactive adolescent rats.
Main Methods:
- Proteomic analysis using LTQ Orbitrap Velos mass spectrometry.
- Transcriptomic analysis using Illumina HiSeq 4000.
- Data processing with Thermo Proteome Discoverer, Scaffold, and Cuffdiff.
Main Results:
- The data article contains raw proteomic and transcriptomic datasets.
- Differential protein and gene expression data are available for analysis.
Conclusions:
- The data provides a molecular basis for understanding social play in adolescent rats.
- This resource can facilitate further research into the neurobiology of social behavior.
