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Updated: Jan 4, 2026

Magnetic Resonance-Guided Stereotaxy for Infusions to the Pig Brain
Published on: March 31, 2023
MRI-guided targeted needle placement during motion using hydrostatic actuators
Samantha Mikaiel1,2, James Simonelli3, Xinzhou Li1,4
1Department of Radiological Sciences, University of California Los Angeles, Los Angeles, California.
Background:
Magnetic resonance imaging (MRI) has unique advantages for guiding interventions, but the narrow space is a major challenge. This study evaluates the feasibility of a remote-controlled hydrostatic actuator system for MRI-guided targeted needle placement.
Methods:
The effects of the hydrostatic actuator system on MR image quality were evaluated. Using a reference step-and-shoot method (SS) and the proposed actuator-assisted method (AA), two operators performed MRI-guided needle placement in targets (n = 12) in a motion phantom.
Results:
The hydrostatic actuator system exhibited negligible impact on MR image quality. In dynamic targets, AA was significantly more accurate and precise than SS, with mean ± SD needle-to-target error of 1.8 ± 1.0 mm (operator 1) and 1.3 ± 0.5 mm (operator 2). AA reduced the insertion time by 50% to 80% and total procedure time by 25%, compared to SS.
Conclusions:
The proposed hydrostatic actuator system may improve accuracy and reduce procedure time for MRI-guided targeted needle placement during motion.
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