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Related Concept Videos

Pleural Disorders: Types and Brief Description01:30

Pleural Disorders: Types and Brief Description

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The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
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The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
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Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
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Endoscopic Studies I: Bronchoscopy and Thoracoscopy01:30

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Endoscopy is a non-surgical medical technique used to examine a person's internal organs and vessels. This lesson will focus on two types of endoscopic studies: bronchoscopy and thoracoscopy.
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Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
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Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
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Extrapleural pneumonectomies for pleural mesothelioma.

Eleonora Faccioli1, Alice Bellini1, Marco Mammana1

  • 1Thoracic Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, Padova University Hospital, Padova, Italy.

Expert Review of Respiratory Medicine
|November 2, 2019
PubMed
Summary

Extra-pleural pneumonectomy (EPP) is a surgical option for malignant pleural mesothelioma (MPM). This review assesses EPP outcomes, highlighting the need for individualized treatment and specialized centers for this complex procedure.

Keywords:
Extra-pleural pneumonectomy (EPP)malignant pleural mesothelioma (MPM)systematic review

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Area of Science:

  • Thoracic Surgery
  • Oncology
  • Malignant Pleural Mesothelioma Research

Background:

  • Malignant pleural mesothelioma (MPM) is an aggressive cancer with limited curative options.
  • Multimodality treatment is standard, but optimal approaches, especially surgical, remain debated.
  • Extra-pleural pneumonectomy (EPP) is a key surgical intervention for MPM.

Purpose of the Study:

  • To review the short- and long-term outcomes of EPP in MPM patients.
  • To evaluate survival rates, recurrence, and perioperative complications associated with EPP.
  • To provide an overview of current EPP results in MPM management.

Main Methods:

  • Systematic review of electronic databases.
  • Inclusion of studies reporting on patients treated with EPP for MPM.
  • Analysis of endpoints including overall survival, disease-free survival, recurrence, mortality, and morbidity.

Main Results:

  • EPP outcomes in MPM patients vary, with ongoing debate regarding its superiority over other surgical techniques.
  • Macroscopic complete resection is a critical goal for surgical interventions in MPM.
  • Perioperative mortality and morbidity are significant considerations for EPP.

Conclusions:

  • The role and efficacy of EPP in MPM management require careful consideration.
  • Individualized treatment strategies are essential due to the availability of alternative therapies and the complexity of EPP.
  • Referral to specialized centers is crucial for patients undergoing complex surgical procedures like EPP for MPM.