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Plasma catecholamines in conscious rabbits after central administration of vasopressin
S M Martin1, T J Malkinson, L G Bauce
1Biology Department, Mount Saint Vincent University, Halifax, N.S., Canada.
Brain Research
|August 2, 1988
Abstract:
Arterial levels of epinephrine (E) were significantly raised for all times sampled, after intracerebroventricular (i.c.v.) injection of arginine vasopressin (AVP) (1 nmol) into conscious rabbits. Venous levels of norepinephrine (NE) were significantly raised within the first 4 min after a similar i.c.v. injection of AVP. The significant increases in arterial E and venous NE correspond in time and therefore could account for changes in heart rate and blood pressure elicited by centrally injected AVP. Therefore, AVP could influence cardiovascular function by increasing the activity of the sympatho-adrenomedullary system.