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Related Concept Videos

Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

820
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

1.0K
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
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Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
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Anorectal Crohn's Disease.

Adam Truong1, Karen Zaghiyan1, Phillip Fleshner1

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Summary

For Crohn's disease (CD) perianal disease, a multidisciplinary approach combining medical and surgical treatments is key. Minimally invasive options, including stem cell therapy, show promise for fistulas, while severe cases may need surgery.

Keywords:
AnalAnorectalCrohn diseaseFistulaIBD

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Area of Science:

  • Gastroenterology and Colorectal Surgery
  • Inflammatory Bowel Disease Research

Background:

  • Perianal disease is a common complication of Crohn's disease (CD).
  • Management often requires a combination of medical and surgical interventions.
  • Current treatments aim to improve quality of life and prevent disease progression.

Purpose of the Study:

  • To review current management strategies for perianal Crohn's disease.
  • To highlight advancements in treatment, particularly for fistulizing CD.
  • To emphasize the importance of a multidisciplinary approach.

Main Methods:

  • Review of existing literature on perianal Crohn's disease management.
  • Analysis of recent clinical trials, focusing on novel therapies.
  • Synthesis of evidence regarding medical, surgical, and combined treatment modalities.

Main Results:

  • Medical therapy is the primary treatment, with surgery reserved for severe or recurrent cases.
  • Minimally invasive surgical options and mesenchymal stem cell therapies show promise for Crohn's-related fistulas.
  • Fecal diversion or proctectomy may be necessary for refractory disease.

Conclusions:

  • A coordinated, multidisciplinary team approach integrating medical and surgical care is essential for optimal perianal CD management.
  • Cessation of proctitis is crucial before considering reversal of fecal diversion.
  • Advancements in minimally invasive techniques and stem cell applications offer new hope for complex cases.