Effects of physical activity and sedentary behaviour on cardiometabolic risk factors and cognitive function in

Yajie Lv1, Li Cai1, Zhaohuan Gui1

  • 1Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, China.

BMJ Open
|November 3, 2019
PubMed

Insights

This study investigates how physical activity (PA) and sedentary behavior (SB) impact children's cardiometabolic health and cognitive function, exploring underlying brain mechanisms through a long-term school-based cohort. Findings will clarify these crucial relationships in youth.

Area of Science:

  • Pediatric Health Research
  • Neuroscience and Cognition
  • Public Health and Epidemiology

Background:

  • Physical activity (PA) and sedentary behavior (SB) are linked to cardiometabolic risk factors and cognitive function, but associations in children are inconsistent.
  • Cardiometabolic risk factors also affect cognitive function, yet research in pediatric populations remains limited.
  • Brain-level mechanisms underlying these associations require further elucidation.

Purpose of the Study:

  • To explore the independent and combined associations of PA and SB with cardiometabolic risk factors and cognitive function in children.
  • To investigate the brain-level mechanisms linking PA and SB to cardiometabolic health and cognitive function in children.
  • To provide evidence for targeted interventions promoting healthy lifestyles in school-aged children.

Main Methods:

  • A school-based prospective cohort study involving 8324 primary school students (aged 7-12) in Guangzhou, China.
  • Data collection includes questionnaires for PA, SB, and cognitive function, anthropometric and biochemical measurements, accelerometry, cognitive tasks, and electroencephalogram (EEG) for event-related potentials.
  • Participants are followed up every two years from 2017 to 2026, with standardized procedures at baseline and follow-up.

Main Results:

  • Data collection is ongoing; results will be published upon study completion.
  • The study design allows for the examination of longitudinal associations and potential causal pathways.
  • Analysis will differentiate effects of PA and SB, and their combined impact on health outcomes.

Conclusions:

  • This study will clarify the complex relationships between physical activity, sedentary behavior, cardiometabolic risk, and cognitive function in children.
  • Understanding the underlying brain mechanisms is crucial for developing effective public health strategies.
  • Findings are expected to inform interventions aimed at improving children's long-term health and cognitive development.
Abstract