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Correction: Bossi et al. Time-Resolved Fluorescence Spectroscopy of Molecularly Imprinted Nanoprobes as an Ultralow Detection Nanosensing Tool for Protein Contaminants. <i>Biosensors</i> 2023, <i>13</i>, 745.

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Molecularly Imprinted Polymers for Cell Recognition.

Stanislav Piletsky1, Francesco Canfarotta2, Alessandro Poma3

  • 1Department of Chemistry, Imperial College, London SW7 2AZ, UK.

Trends in Biotechnology
|November 4, 2019
PubMed
Summary
This summary is machine-generated.

Molecularly imprinted polymers (MIPs) are advancing, with new epitope imprinting methods enabling nanoparticle creation for cell targeting. These materials show promise in imaging, drug delivery, diagnostics, and tissue engineering applications.

Keywords:
cell recognitionepitopesmolecularly imprinted polymers (MIPs)sensorsstem cellstargeted delivery

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Area of Science:

  • Polymer Science
  • Biotechnology
  • Nanotechnology

Background:

  • Molecularly imprinted polymers (MIPs) have evolved significantly over 50 years.
  • Cellular targets present unique challenges for molecular imprinting techniques.
  • Historically, microprinting dominated, but recent advancements favor epitope imprinting for nanoparticle synthesis.

Purpose of the Study:

  • To review various molecular imprinting approaches for cell targeting.
  • To highlight the applications of cell-imprinted materials.
  • To discuss advancements in MIP synthesis relevant to cell imprinting.

Main Methods:

  • Epitope imprinting for generating MIP nanoparticles (NPs).
  • Solid-phase MIP synthesis techniques.
  • Description of various cell imprinting methodologies.

Main Results:

  • Shift from microprinting to epitope imprinting for cell targeting.
  • Development of solid-phase synthesis to overcome production challenges.
  • Demonstration of MIP NPs' potential in diverse biomedical fields.

Conclusions:

  • Cell imprinting with MIPs is a rapidly developing field.
  • MIP nanoparticles offer versatile platforms for biomedical applications.
  • Advancements in synthesis are crucial for realizing the potential of cell-targeted MIPs.