High foliar affinity cellulose for the preparation of efficient and safe fipronil formulation

In this work, fipronil was encapsulated within ethanediamine-modified carboxymethylcellulose (ACMC) to prepare an efficient and environmentally safe pesticide formulation (ACMCF). The chemical structure, morphology, foliar adhesion, bioactivity, and soil mobility of ACMCF were also systematically investigated. Results demonstrated that fipronil was encapsulated to form microcapsules successfully. Compared with the traditional fipronil emulsion (FE), ACMCF had a relatively high retention rate on cucumber and peanut leaves. The acute contact toxicity of ACMCF (LD₅₀ = 0.151 μg a.i./bee) toward Apis mellifera was far lower than that of FE (LD₅₀ = 0.00204 μg a.i./bee). Biological activity surveys confirmed that ACMCF has insecticidal ability against Plutella xylostella similar to that of FE. Moreover, the leaching and migration properties of ACMCF in three different kinds soils were weaker than those of FE. These results imply that ACMCF has promising application potential in increasing the effective utilization of fipronil and reducing risk to non-target organisms and the environment.