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Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
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Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus

Published on: January 28, 2019

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Measurement of coverage, compliance and determinants of uptake in a publicly funded rotavirus vaccination programme:

Ellen Rafferty1, Xiaoyan Guo2, Bruce McDonald2

  • 1Nursing, University of Alberta, Edmonton, Alberta, Canada.

BMJ Open
|November 4, 2019
PubMed

Insights

Alberta

Area of Science:

  • Pediatric infectious diseases
  • Public health vaccination programs
  • Health services research

Background:

  • Alberta implemented a universal rotavirus vaccination program in June 2015.
  • The program uses Rotarix (RV1) with doses at 2 and 4 months.
  • Vaccination had age restrictions for first and second doses.

Purpose of the Study:

  • To assess rotavirus vaccination coverage and schedule compliance in Alberta.
  • To identify factors associated with rotavirus vaccine uptake.
  • To compare rotavirus vaccine coverage with other childhood immunizations.

Main Methods:

  • Retrospective cohort study.
  • Utilized linked administrative health data for 66,689 children born between June 2015 and August 2016.
  • Analyzed first and second dose coverage, schedule non-compliance, and factors influencing vaccination status.

Main Results:

  • One-dose rotavirus vaccine coverage was 87%, and two-dose coverage was 83%.
  • Coverage was lower than diphtheria-tetanus-pertussis-polio-Haemophilus influenzae type b (DTaP) vaccine (92% for two doses).
  • Socioeconomic factors like income, location, and household size were associated with rotavirus vaccine uptake.

Conclusions:

  • High compliance with the rotavirus vaccine schedule was observed.
  • Rotavirus vaccine coverage lagged behind DTaP vaccination.
  • Socioeconomic disparities in uptake raise concerns for vulnerable populations, including low-income and rural communities.
Abstract

Keywords:
coveragedeterminants of uptakeimmunizationrotavirusvaccination

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