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Updated: Jan 4, 2026

Author Spotlight: Uncovering the Role of Mitochondrial Calcium Phosphate in Heart Failure and Bioenergetics
Published on: August 23, 2024
Mitochondria and Cardiovascular Disease: A Brief Account
Michela Pecoraro1, Aldo Pinto1, Ada Popolo1
1Department of Pharmacy, University of Salerno, Fisciano (SA), Italy.
Abstract:
Mitochondria represent the heart unit of the cardiac cell because they are involved in ATP production and in the transfer to the contractile apparatus. Furthermore, mitochondria modulate Ca2+ homeostasis, manage redox status, and regulate response to cellular and environmental stresses. Abnormalities in mitochondrial organelle structure and function have been observed in many cardiovascular diseases, such as ischemic cardiomyopathy, heart failure, and stroke, and in drug-induced cardiomyopathies. This review summarizes the recent literature in this field.
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