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In Vivo Mouse Model of Spinal Implant Infection
Published on: June 23, 2020
Management of Pyogenic Spinal Infection, review of literature
Ahmed Aljawadi1, Noman Jahangir1, Ana Jeelani1
1Trauma and Orthopaedics, Manchester Foundation Trust, Southmoor Rd, Wythenshawe, Manchester, M23 9LT, UK.
Objective:
To evaluate the available evidence for the management of Pyogenic Spinal Infection (PSI).
Methods And Results:
A comprehensive search for the relevant literature published between 1990 and 2018 to evaluate the management of PSI was conducted.Nonoperative management of carefully selected patients for an adequate duration of antibiotics can result in satisfactory outcomes with low recurrence rate. When there is an indication for surgery, posterior approach, with or without debridement of infected tissue reported to be associated with good outcomes.
Conclusion:
Studies with larger sample sizes and longer duration of follow up are recommended to formulate more comprehensive evidence.
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