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Quantitative analysis of regional systolic function with left ventricular aneurysm
1Department of Surgery, Columbia University College of Physicians and Surgeons, New York 10032.
Circulation
|October 1, 1988
Summary
Standard surgical repair of left ventricular aneurysms (LVA) shows improved regional systolic function. This study quantifies regional function changes after LVA resection, aiding surgical approach assessment.
Area of Science:
- Cardiovascular Surgery
- Cardiac Imaging
- Heart Mechanics
Background:
- Left ventricular aneurysm (LVA) is poorly understood, often leading to heart failure unresponsive to standard treatment.
- Current methods inadequately assess the impact of surgical interventions on left ventricular function.
Purpose of the Study:
- To quantitatively define regional systolic function in LVA patients.
- To assess acute changes in regional function following standard LVA repair.
Main Methods:
- Seven patients with anteroapical LVA underwent resection.
- Intraoperative 2D echocardiography was used before and after surgery.
- Regional myocardial area, perimeter, and wall thickness were analyzed in octants.
Main Results:
- Pre-resection, the apex showed anteroseptal paradox and distorted geometry.
- Significant isovolumetric thinning occurred in the aneurysm and bordering segments (-17 +/- 5%).
- Late-systolic thickening was observed post-resection, indicating functional improvement.
Conclusions:
- Standard LVA resection can acutely improve regional systolic function.
- Quantitative echocardiography provides valuable assessment of functional changes post-LVA repair.
- Further research is needed to optimize surgical strategies for LVA.