Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Coronary collateral development after acute myocardial infarction.

M Fujita1, S Sasayama, M Ejiri

  • 1Second Department of Internal Medicine, Toyama Medical and Pharmaceutical University, Japan.

Clinical Cardiology
|August 1, 1988
PubMed
Summary

Coronary collateral circulation significantly improves after a first myocardial infarction, particularly in right coronary artery obstructions. These vital collateral vessels develop within a month, independent of coronary artery disease severity.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A transesophageal echocardiographic study on risk factors for stroke in elderly patients with atrial fibrillation: a comparison with younger patients.

Chest·2001
Same author

Respiratory modulation of muscle sympathetic nerve activity in patients with chronic heart failure.

Circulation·2001
Same author

Instability of anticoagulation intensity contributes to occurrence of ischemic stroke in patients with non-rheumatic atrial fibrillation.

Japanese circulation journal·2001
Same author

Relation of fibrillatory wave amplitude with hemostatic abnormality and left atrial appendage dysfunction in patients with chronic nonrheumatic atrial fibrillation.

Japanese circulation journal·2001
Same author

Modulation of ventricular repolarization and R-R interval is altered in patients with globally impaired cardiac 123I-MIBG uptake.

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·2001
Same author

[Autonomic function and circulatory failure].

Nihon rinsho. Japanese journal of clinical medicine·2000

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Vascular Biology

Background:

  • Coronary collateral circulation plays a crucial role in myocardial salvage during acute myocardial infarction.
  • Understanding the development and extent of collateralization post-infarction is vital for patient outcomes.
  • Previous studies have explored factors influencing collateral formation, but timing and territory-specific differences require further elucidation.

Purpose of the Study:

  • To evaluate the extent of coronary collateral circulation in patients following their first myocardial infarction.
  • To compare collateral visualization between right coronary artery and left anterior descending artery occlusions.
  • To investigate the relationship between the time interval from symptom onset to angiography and collateral development.

Related Experiment Videos

Main Methods:

  • Coronary angiography was performed in 31 patients without prior angina during the convalescent phase of their first myocardial infarction.
  • Collateral visualization was quantified using a collateral index.
  • Patients were stratified based on the location of the infarct-related coronary artery (right coronary artery vs. left anterior descending artery).

Main Results:

  • Significantly greater collateral visualization (collateral index) was observed in patients with right coronary artery involvement compared to those with left anterior descending artery obstruction (2.1 +/- 1.1 vs. 1.2 +/- 1.0, p < 0.05).
  • The time interval from symptom onset to angiographic evaluation did not influence collateral visualization or coronary artery disease severity.
  • Findings suggest collateral vessels proliferate within one month post-myocardial infarction.

Conclusions:

  • Collateral vessels develop robustly within one month after acute myocardial infarction, irrespective of the extent of underlying coronary artery disease.
  • The degree of collateral visualization appears dependent on the perfusion territory of the infarct-related coronary artery.
  • Right coronary artery occlusions are associated with more extensive collateralization compared to left anterior descending artery occlusions in the early post-infarction period.