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Nanotechnology in Oral Cavity Carcinoma: Recent Trends and Treatment Opportunities
Francesca De Felice1, Costanza Cavallini2, Alberta Barlattani3
1Department of Radiotherapy, Policlinico Umberto I, "Sapienza" University of Rome, 00161 Rome, Italy. fradefelice@hotmail.it.
Abstract:
Oral cavity carcinoma (OCC) remains an ongoing public health problem. Emerging nanotechnology provides alternative treatment approaches. This review covers the up-to-date literature in the human OCC treatment field. We explored the growing body of evidence to reveal novel and highly promising diagnostic and therapeutic applications of nanotechnology in this field. Various types of nanoparticles have been tested for applications in OCC. Imaging modalities in addition to nanocarriers are discussed. The encouraging contribution of lymphotropic nanoparticles contrast in the diagnosis of metastatic cervical lymph nodes needs to be confirmed. The development of the sentinel lymph node procedure and photodynamic therapy may lead to breakthrough therapies in order improve clinical outcomes and quality of life. In this perspective, cancer nanotechnology has the potential to revolutionize the treatment of OCC patients.
Insights
Nanotechnology offers promising new ways to diagnose and treat oral cavity carcinoma (OCC). Research shows various nanoparticles and advanced imaging techniques could revolutionize OCC patient care and improve outcomes.
Area of Science:
- Oncology
- Nanotechnology
- Biomedical Engineering
Background:
- Oral cavity carcinoma (OCC) presents a persistent global health challenge.
- Conventional treatments for OCC have limitations, necessitating novel therapeutic strategies.
- Nanotechnology is emerging as a transformative field in cancer research and treatment.
Purpose of the Study:
- To review current literature on nanotechnology applications for human oral cavity carcinoma.
- To explore novel diagnostic and therapeutic uses of nanotechnology in OCC.
- To identify potential breakthroughs for improving clinical outcomes and patient quality of life.
Main Methods:
- Comprehensive literature search on nanotechnology in oral cavity carcinoma treatment.
- Analysis of various nanoparticle types and their applications in OCC.
- Review of advanced imaging modalities and nanocarrier systems.
Main Results:
- Diverse nanoparticles show potential for OCC diagnosis and therapy.
- Nanotechnology-based imaging and drug delivery systems are under investigation.
- Lymphotropic nanoparticles and photodynamic therapy show promise for improved diagnostics and treatment.
Conclusions:
- Cancer nanotechnology holds significant potential to revolutionize OCC treatment.
- Further research is needed to confirm the efficacy of lymphotropic nanoparticles in diagnosing metastatic lymph nodes.
- Advancements in nanomedicine could lead to breakthrough therapies improving patient survival and quality of life.
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