Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

siRNA - Small Interfering RNAs02:30

siRNA - Small Interfering RNAs

18.3K
Small interfering RNAs, or siRNAs, are short regulatory RNA molecules that can silence genes post-transcriptionally, as well as the transcriptional level in some cases. siRNAs are important for protecting cells against viral infections and silencing transposable genetic elements.
In the cytoplasm, siRNA is processed from a double-stranded RNA, which comes from either endogenous DNA transcription or exogenous sources like a virus. This double-stranded RNA is then cleaved by the...
18.3K
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

900
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
900
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

8.6K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
8.6K
Drugs that Stabilize Microtubules01:15

Drugs that Stabilize Microtubules

2.6K
Microtubules are dynamic structures that undergo cycles of catastrophe and rescue. The microtubules play a central role in cell division by forming the spindle apparatus for segregating the chromosomes. This makes them ideal targets for regulating dividing cells in tumors and malignant cancer cells. Microtubule stabilizing drugs help stabilize the microtubule formation and promote its polymerization. Paclitaxel was the first microtubule stabilizing agent used as anticancer drug in chemotherapy...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Precursor-dependent optical and structural properties of eleven NIR-emissive graphene quantum dots for bioimaging applications.

2d materials·2026
Same author

Therapeutic opportunities for nanomedicine with hollow one-dimensional silicon nanotubes.

Nanomedicine (London, England)·2025
Same author

Impact of Cetyl-Containing Ionic Liquids on Metal Halide Perovskite Structure and Photoluminescence.

Nanomaterials (Basel, Switzerland)·2025
Same author

Holistic Investigation of Graphene Quantum Dot Endocytosis.

Small (Weinheim an der Bergstrasse, Germany)·2025
Same author

Förster Resonance Energy Transfer and Enhanced Emission in Cs<sub>4</sub>PbBr<sub>6</sub> Nanocrystals Encapsulated in Silicon Nano-Sheets for Perovskite Light Emitting Diode Applications.

Nanomaterials (Basel, Switzerland)·2024
Same author

Five near-infrared-emissive graphene quantum dots for multiplex bioimaging.

2d materials·2024

Related Experiment Video

Updated: Jan 4, 2026

Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube SWCNT-delivered MALAT1 Antisense Oligos
07:24

Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube SWCNT-delivered MALAT1 Antisense Oligos

Published on: December 13, 2018

6.8K

Silicon Nanotubes as Potential Therapeutic Platforms.

Nguyen T Le1, Yuan Tian2, Roberto Gonzalez-Rodriguez3

  • 1Department of Chemistry and Biochemistry, Texas Christian University, Fort Worth, TX 76129, USA. nguyen.t.le@tcu.edu.

Pharmaceutics
|November 6, 2019
PubMed
Summary

Silicon nanotubes (SiNTs) offer a promising new platform for therapeutic applications due to their tunable structures and biodegradability. Their surfaces can be functionalized for drug delivery, cell labeling, and nanoparticle scaffolding, paving the way for advanced medical treatments.

Keywords:
drug deliverysilicon nanotubessurface chemistry

More Related Videos

Porous Silicon Microparticles for Delivery of siRNA Therapeutics
08:31

Porous Silicon Microparticles for Delivery of siRNA Therapeutics

Published on: January 15, 2015

11.4K
Designing Porous Silicon Films as Carriers of Nerve Growth Factor
10:12

Designing Porous Silicon Films as Carriers of Nerve Growth Factor

Published on: January 25, 2019

10.1K

Related Experiment Videos

Last Updated: Jan 4, 2026

Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube SWCNT-delivered MALAT1 Antisense Oligos
07:24

Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube SWCNT-delivered MALAT1 Antisense Oligos

Published on: December 13, 2018

6.8K
Porous Silicon Microparticles for Delivery of siRNA Therapeutics
08:31

Porous Silicon Microparticles for Delivery of siRNA Therapeutics

Published on: January 15, 2015

11.4K
Designing Porous Silicon Films as Carriers of Nerve Growth Factor
10:12

Designing Porous Silicon Films as Carriers of Nerve Growth Factor

Published on: January 25, 2019

10.1K

Area of Science:

  • Nanotechnology
  • Materials Science
  • Biomedical Engineering

Background:

  • Silicon nanotubes (SiNTs) represent a novel nanoscale silicon architecture.
  • Mesoporous silicon's therapeutic and biosensing potential is established, but SiNT applications are emerging.
  • This review focuses on SiNT properties relevant to therapeutic uses.

Purpose of the Study:

  • To review the fundamental properties of SiNTs for therapeutic applications.
  • To highlight the synthetic control over SiNT structure and dissolution behavior.
  • To summarize surface functionalization strategies and potential applications.

Main Methods:

  • Review of existing literature on SiNT fabrication and characterization.
  • Analysis of in vitro dissolution studies to assess biodegradability.
  • Summary of surface functionalization techniques and conjugation strategies.

Main Results:

  • SiNT structure can be precisely tuned through synthetic control.
  • In vitro dissolution studies provide insights into SiNT biodegradability.
  • Diverse functional moieties can be attached to SiNT surfaces for various applications.
  • SiNTs can be loaded with species for magnetic field-assisted drug delivery.

Conclusions:

  • SiNTs exhibit promising properties for therapeutic platforms.
  • Tunable structure, biodegradability, and functionalizability are key advantages.
  • Future research is expected to expand SiNT applications in medicine.