Related Experiment Videos
Main manifestations of carditis in diffuse connective tissue diseases in children
L A Isaeva1, V M Deliagin, L K Bazhenova
1Clinic of Children Diseases, I. M. Sechenov 1st Moscow Medical Institute, USSR.
Insights
Echography revealed characteristic heart changes in 238 children with diffuse connective tissue diseases. Specific hemodynamic alterations were observed, differing between systemic lupus erythematosus, dermatomyositis, and systemic sclerosis.
Area of Science:
- Pediatric Rheumatology
- Cardiology
- Medical Imaging
Background:
- Diffuse connective tissue diseases (DCTDs) can affect multiple organ systems, including the cardiovascular system.
- Early detection of cardiac involvement in pediatric DCTDs is crucial for management.
- Echocardiography is a non-invasive tool for assessing cardiac structure and function.
Purpose of the Study:
- To investigate the presence and nature of cardiac morphofunctional changes in children with DCTDs.
- To identify characteristic hemodynamic alterations associated with specific DCTDs in pediatric patients.
Main Methods:
- Clinical examination of 238 children diagnosed with diffuse connective tissue diseases.
- Utilization of echocardiography to assess cardiac morphology and function.
- Analysis of hemodynamic parameters to identify specific patterns of cardiac dysfunction.
Main Results:
- Characteristic morphofunctional cardiac changes were identified in children with collagen diseases.
- Distinct hemodynamic disturbances were observed: contraction issues in systemic lupus erythematosus and dermatomyositis.
- Relaxation disturbances were predominantly noted in patients with systemic scleroderma.
Conclusions:
- Echocardiography is valuable for detecting cardiac involvement in pediatric DCTDs.
- Specific patterns of cardiac dysfunction can help differentiate between various DCTDs in children.
- Understanding these cardiac manifestations is essential for tailored therapeutic strategies.
Abstract:
238 children with diffuse connective tissue diseases were clinically examined with the use of echography. The presence was documented of characteristic morphofunctional changes in the heart in collagen diseases. Characteristic haemodynamic changes (predominantly contraction disturbances in systemic lupus erythematodes and dermatomyositis, and relaxation disturbances in systemic scleroderma) were identified.