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Related Experiment Videos

Red/orange person syndrome.

D J Gross1, R P Dellinger

  • 1University of Arkansas for Medical Sciences, Little Rock.

Cutis
|September 1, 1988
PubMed
Summary
This summary is machine-generated.

A patient

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Area of Science:

  • Pharmacology
  • Toxicology
  • Dermatology

Background:

  • Rifampicin is a crucial antibiotic for treating tuberculosis.
  • Overdose cases are rare, but can lead to significant side effects.

Observation:

  • A patient presented with sudden onset of orange skin discoloration.
  • This occurred after ingesting a large quantity of rifampicin (approximately 12,000 mg).

Findings:

  • The orange skin coloration resolved within 24 hours.
  • Persistent orange discoloration of urine and tears was noted for several days post-ingestion.

Implications:

  • This case highlights a rare but visually striking side effect of rifampicin overdose.
  • It underscores the importance of monitoring for toxic effects even with short-term, high-dose exposures.