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Related Experiment Video

Updated: Jan 4, 2026

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Multiple Myeloma Breast Involvement: A Case Report.

Heba O E Ali1, Zafar Nasir2, Ahmed M S M Marzouk3,4

  • 1Consultant Breast Radiology, Altnagelvin Area Hospital, WHSC Trust, Glenshane Rd, Londonderry BT47 6SB, UK.

Case Reports in Radiology
|November 6, 2019
PubMed
Summary
This summary is machine-generated.

Multiple Myeloma rarely affects the breast, presenting diagnostic challenges due to similar symptoms to other breast diseases. This case highlights diagnosing breast masses as extraosseous Multiple Myeloma, not primary breast cancer metastasis.

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Area of Science:

  • Oncology
  • Hematology
  • Radiology

Background:

  • Multiple Myeloma (MM) is a rare plasma cell malignancy.
  • Breast involvement by MM is exceptionally uncommon, posing diagnostic difficulties.
  • Clinical and radiological presentations of breast MM mimic primary or metastatic breast cancer.

Observation:

  • A patient presented with palpable breast masses.
  • Initial assessment suggested metastatic breast cancer due to multiple spinal lesions.
  • Further investigation revealed the breast masses to be extraosseous Multiple Myeloma.

Findings:

  • The breast masses were histopathologically confirmed as extraosseous Multiple Myeloma.
  • The patient's spinal lesions were also attributed to the underlying myeloma.
  • This case underscores the importance of considering rare differentials in breast pathology.

Implications:

  • Highlights the diagnostic challenges of extraosseous Multiple Myeloma in the breast.
  • Emphasizes the need for thorough investigation beyond initial assumptions of metastasis.
  • Contributes to understanding the diverse presentations of plasma cell neoplasms.