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Related Experiment Videos

Pattern- and flash-evoked potentials in patients with dissociated vertical deviation.

A Kriss1, C Timms, J Elston

  • 1Hospital for Sick Children, London, UK.

Documenta Ophthalmologica. Advances in Ophthalmology
|July 1, 1988
PubMed
Summary
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Children with dissociated vertical deviation showed reduced pattern visual evoked potentials. Unlike albinism, no anomalous flash responses or pattern reversal asymmetries were observed in these patients.

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Pediatric Medicine

Background:

  • Dissociated vertical deviation (DVD) is a strabismus characterized by upward movement of one eye.
  • The neurophysiological underpinnings of DVD are not fully understood.
  • Previous studies have explored visual evoked potentials (VEPs) in various ocular motility disorders.

Purpose of the Study:

  • To investigate pattern and flash visual evoked potentials in children diagnosed with dissociated vertical deviation.
  • To compare VEP responses in DVD patients with age-matched controls.
  • To determine if DVD exhibits similar VEP anomalies as seen in albinism.

Main Methods:

  • Recording of pattern reversal and flash evoked potentials in 13 children with DVD.
  • Comparison of VEP amplitudes and latencies between DVD patients and a control group.

Related Experiment Videos

  • Analysis of monocular and binocular responses to both pattern and flash stimuli.

    • Main Results:

    • No evidence of anomalous pattern reversal half-field stimulation responses in DVD patients.
    • No significant asymmetries in flash evoked potentials were detected, unlike findings in albinism.
    • Significantly smaller monocular and binocular pattern evoked potentials were observed in children with DVD compared to controls.

    Conclusions:

    • Dissociated vertical deviation is associated with reduced pattern VEP amplitudes.
    • The VEP findings in DVD differ from those typically seen in albinism.
    • VEP testing may offer insights into the visual processing deficits in DVD.