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Updated: Jan 4, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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Psoriasis and alcohol.

Caroline Svanström1,2, Sol-Britt Lonne-Rahm1, Klas Nordlind2

  • 1Department of Dermatology, Mälarsjukhuset, Eskilstuna, Sweden.

Psoriasis (Auckland, N.Z.)
|November 6, 2019
PubMed
Summary
This summary is machine-generated.

Alcohol consumption is common in psoriasis patients and affects neurotransmitter systems. These systems may influence psoriasis inflammation, suggesting future therapies targeting these neurobiological pathways.

Keywords:
alcoholneurotransmittersprurituspsoriasis

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Area of Science:

  • Dermatology
  • Neuroscience
  • Pharmacology

Background:

  • Psoriasis is a chronic inflammatory skin condition.
  • Alcohol consumption is frequently observed in individuals with psoriasis.
  • Alcohol impacts neurobiological signaling pathways, including dopaminergic, serotonergic, and tachykinergic systems.

Purpose of the Study:

  • To explore the connection between alcohol consumption, neurobiological signaling, and inflammatory processes in psoriasis.
  • To identify potential therapeutic targets within neurotransmitter networks relevant to both alcohol intake and psoriasis.

Main Methods:

  • Review of existing literature on alcohol's effects on neurobiology and inflammation.
  • Analysis of the role of neurotransmitters in reward and drug-seeking behaviors.
  • Examination of the interplay between neurobiological systems and inflammatory mechanisms in skin diseases.

Main Results:

  • Alcohol intake affects key neurotransmitter systems implicated in reward and addiction.
  • These affected neurotransmitter systems may play a role in the inflammatory processes characteristic of psoriasis.
  • A significant overlap exists between the neurobiological pathways influenced by alcohol and those involved in psoriasis pathogenesis.

Conclusions:

  • Neurotransmitter networks represent a potential therapeutic avenue for managing psoriasis.
  • Targeting these shared pathways could address both alcohol use and inflammatory symptoms in psoriasis patients.
  • Future research should focus on elucidating the precise mechanisms linking alcohol-induced neurobiological changes to psoriasis inflammation.