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Updated: Jan 4, 2026

08:34
A Rapid and Quantitative Fluorimetric Method for Protein-Targeting Small Molecule Drug Screening
Published on: October 16, 2015
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A flavonoid-based fluorescent probe enables the accurate quantification of human serum albumin by minimizing the
Kangning Zhu1, Taoyuze Lv2, Tianyi Qin2
1Shenzhen Key Laboratory of Polymer Science and Technology, College of Materials Science and Engineering, Shenzhen University, Shenzhen, 518060, P. R. China. bliu@szu.edu.cn and Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, 325001, P. R. China.
Abstract:
We herein provide a simple design strategy to improve the sensing specificity towards human serum albumin by incorporating a nitrobenzene quencher into a traditional polarity-sensitive probe in responding to the interference from blood lipids.

