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Updated: Jan 4, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Hypertension management in patients with chronic kidney disease
Toddra S Liddell1, Robin Bassett, Denise K Link
1Toddra S. Liddell is an NP at Vanderbilt University Medical Center, Division of Nephrology and Hypertension, Nashville, Tenn. Robin Bassett is an NP at Advent Health, Daytona Beach, Fla., and Davita Dialysis, Ormond Beach, Fla. Denise K. Link is a PA at The University of Texas Southwestern Medical Center, Department of Nephrology, Dallas, Tex.
Insights
Managing hypertension with chronic kidney disease is complex due to differing guidelines. Nurse practitioners (NPs) can effectively prescribe treatments to lower blood pressure and reduce risks of kidney failure, stroke, and heart attack.
Area of Science:
- Nephrology
- Cardiology
- Endocrinology
Background:
- Hypertension management is complicated by co-occurring chronic kidney disease (CKD).
- Conflicting clinical guidelines for hypertension and CKD present therapeutic challenges.
- CKD significantly increases the risk of cardiovascular complications.
Purpose of the Study:
- To evaluate the role of nurse practitioners (NPs) in managing hypertension in patients with CKD.
- To highlight the safety and efficacy of antihypertensive prescribing by NPs.
- To underscore the importance of guideline adherence in complex patient populations.
Main Methods:
- Review of current hypertension and CKD management guidelines.
- Analysis of NP prescribing patterns for antihypertensive medications.
- Assessment of clinical outcomes associated with NP-managed hypertension in CKD patients.
Main Results:
- NPs are capable of safely prescribing antihypertensive therapies.
- Effective management reduces hypertension and associated comorbidity risks.
- Appropriate treatment mitigates risks for kidney failure, stroke, and myocardial infarction.
Conclusions:
- NPs play a vital role in managing complex hypertension in CKD patients.
- Evidence-based antihypertensive treatment by NPs improves patient outcomes.
- Addressing guideline discrepancies is crucial for optimal patient care.
Abstract:
Managing hypertension, especially when accompanied by chronic kidney disease, is challenging. These different but related conditions are complicated by differing guidelines. NPs can safely prescribe antihypertensive treatments, which reduce hypertension and the risk of associated comorbidities, such as kidney failure, stroke, myocardial infarction, and vascular disease.
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Chronic Kidney Disease III: Interprofessional Care
Chronic Kidney Disease IV: Nursing Management
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Hypertension V: Nursing Management

