CDK4/6 Inhibitor Biomarker Research: Are We Barking Up the Wrong Tree?
Meenakshi Anurag1, Svasti Haricharan2, Matthew J Ellis3
1Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas.
Abstract:
CDK4/6 inhibitors have emerged as a significant advance for the treatment of patients with advanced estrogen receptor-positive breast cancer. However, the identification of predictive markers that optimize their use is proving harder than expected. In this commentary we advocate for unbiased discovery and a collaborative approach across trials.See related article by Finn et al., p. 110.
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