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[Drug treatment of heart failure in chronic kidney disease]

Nikolaus Marx1

  • 1Medizinische Klinik I - Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum Aachen, RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Deutschland. nmarx@ukaachen.de.

Der Internist
|November 7, 2019
PubMed

Insights

Patients with chronic kidney disease (CKD) face higher heart failure risks and poorer outcomes. This review covers standard heart failure drug treatments and specific considerations for CKD patients.

Area of Science:

  • Nephrology
  • Cardiology
  • Pharmacology

Background:

  • Patients with chronic kidney disease (CKD) have a significantly elevated risk of developing heart failure.
  • The coexistence of heart failure and CKD portends a worse prognosis for affected individuals.

Purpose of the Study:

  • To summarize the current standard drug therapies for heart failure.
  • To discuss unique considerations for managing heart failure in patients with CKD.

Main Methods:

  • Literature review of current heart failure pharmacotherapy guidelines.
  • Analysis of studies addressing drug treatment in comorbid CKD and heart failure.

Main Results:

  • Standard heart failure drug treatments are detailed.
  • Specific challenges and adjustments for drug selection and dosing in CKD patients are highlighted.

Conclusions:

  • Effective management of heart failure in CKD requires careful consideration of renal function.
  • Optimizing pharmacotherapy is crucial for improving outcomes in this high-risk population.

Keywords:
Adrenergic beta-antagonistsAngiotensin receptor neprilysin inhibitorsAngiotensin-converting enzyme inhibitorsCKDHeart failure

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