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Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Related Experiment Video

Updated: Jan 4, 2026

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
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[Refractive shift after glaucoma surgery].

S Yu Petrov1, A A Antonov1, K S Avetisov1

  • 1Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021.

Vestnik Oftalmologii
|November 7, 2019
PubMed
Summary

Glaucoma surgery can unexpectedly cause with-the-rule astigmatism by steepening the cornea. The exact reasons for this refractive change after glaucoma surgery remain unclear.

Keywords:
astigmatismglaucomarefractionsinus trabeculectomy

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Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
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Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Refractive Errors

Background:

  • Glaucoma surgery can alter ocular biometric features, including corneal shape.
  • Changes in corneal curvature significantly impact refractive outcomes.
  • Previous research has explored astigmatism post-glaucoma surgery, but the primary cause is debated.

Purpose of the Study:

  • To investigate the impact of glaucoma surgery on corneal curvature and astigmatism.
  • To elucidate the underlying mechanisms contributing to refractive shifts after glaucoma surgery.

Main Methods:

  • Analysis of biometric changes following glaucoma surgery.
  • Review of existing literature on corneal astigmatism post-glaucoma procedures.
  • Exploration of potential pathogenetic factors including wound healing and surgical techniques.

Main Results:

  • Glaucoma surgery, contrary to expectations, leads to corneal steepening and the development of with-the-rule astigmatism.
  • Factors such as conjunctival incisions, sutures, intraocular pressure, and wound healing characteristics are implicated.
  • Scleral wound healing, resembling connective tissue aging, may play a role in corneal shape changes.

Conclusions:

  • Glaucoma surgery induces specific changes in corneal curvature, resulting in with-the-rule astigmatism.
  • While several factors are associated, the precise mechanism driving corneal astigmatism post-glaucoma surgery requires further investigation.