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Updated: Jan 4, 2026

Assessment and Characterization of Hyaloid Vessels in Mice
Published on: May 15, 2019
[Asteroid hyalosis].
S I Kharlap1, A R Salikhova1, N V Miroshnik1
1Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021.
This review examines asteroid hyalosis, a vitreous condition, detailing its history, pathogenesis, and composition. A new digital ultrasound method is proposed for intravital assessment of vitreous changes.
Area of Science:
- Ophthalmology
- Vitreoretinal Medicine
- Biochemistry
Background:
- Asteroid hyalosis is characterized by phospholipid mineral deposits within the vitreous humor.
- Understanding its historical study provides context for current research.
- Pathogenesis and occurrence are key aspects of vitreous body alterations.
Purpose of the Study:
- To analyze existing clinical and experimental data on vitreous changes in asteroid hyalosis.
- To evaluate the current understanding of the forms and elemental composition of vitreous deposits.
- To introduce a novel method for intravital assessment of the vitreous body in affected patients.
Main Methods:
- Comprehensive review of historical and contemporary clinical and experimental studies.
- Analysis of data on the elemental composition of phospholipid mineral sedimentation.
- Application of digital ultrasound for macrostructure and state assessment of the vitreous body.
Main Results:
- Current knowledge on the forms and elemental composition of phospholipid deposits in asteroid hyalosis is evaluated.
- The limitations of intravital assessment methods are discussed.
- A digital ultrasound technique is proposed for examining vitreous macrostructure and hyaloid tracts.
Conclusions:
- Further research is needed to fully elucidate the pathogenesis and composition of asteroid hyalosis.
- Digital ultrasound shows promise as a non-invasive tool for evaluating vitreous changes in asteroid hyalosis.
- Improved intravital assessment methods are crucial for managing this condition.
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