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Assessing Bacterial Invasion of Cardiac Cells in Culture and Heart Colonization in Infected Mice Using Listeria monocytogenes
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Assessing Bacterial Invasion of Cardiac Cells in Culture and Heart Colonization in Infected Mice Using Listeria monocytogenes

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Resolution of atrial-ventricular block secondary to Listeria monocytogenes with antimicrobials

Anuoluwapo Shobayo1, Krishna Kommineni1, Kavita Sharma1

  • 1The Department of Internal Medicine, Maimonides Medical Center, Brooklyn, New York, USA.

Idcases
|November 7, 2019
PubMed

Insights

Listeria endocarditis can cause serious complications like heart block. This case shows that antimicrobial treatment alone successfully resolved heart block in a patient with Listeria endocarditis.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Microbiology

Background:

  • Listeria endocarditis is a rare condition with high mortality.
  • Optimal treatment strategies for Listeria endocarditis remain unclear.
  • Atrial-ventricular (AV) block is a serious complication of infective endocarditis.

Observation:

  • A 66-year-old female with prosthetic valves developed Listeria monocytogenes infective endocarditis.
  • The patient presented with atrial-ventricular (AV) block.
  • The suspected source of infection was consumption of contaminated cold-cut sandwiches.

Findings:

  • Infective endocarditis caused by Listeria monocytogenes was treated with a 6-week course of ampicillin and gentamicin.
  • The antimicrobial therapy successfully eradicated the Listeria infection.
  • The atrial-ventricular (AV) block resolved following antimicrobial treatment.
  • Perivalvular abscesses were suggested as the cause of the AV block.

Implications:

  • This is the first reported case of AV block secondary to listeriosis resolving with antimicrobial treatment alone.
  • Antimicrobial therapy may be a sufficient treatment for AV block in Listeria endocarditis.
  • Further research is needed to confirm these findings and guide clinical practice for Listeria endocarditis with AV block.

Keywords:
Atrial-ventricular blockBioprosthetic valveInfective endocarditisL. monocytogenes

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