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Updated: Jan 4, 2026

Author Spotlight: Eco-Friendly Pest Management Using Entomopathogenic Fungi Against Mustard Aphids
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Author Spotlight: Eco-Friendly Pest Management Using Entomopathogenic Fungi Against Mustard Aphids

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[Giant aphthae].

Fatima-Zahra Agharbi1

  • 1Centre Hospitalier Régional Tétouan, Tétouan, Maroc.

The Pan African Medical Journal
|November 7, 2019
PubMed
Summary
This summary is machine-generated.

Recurrent aphthae, especially bipolar types, can indicate Behçet's disease, a systemic condition. Early diagnosis and treatment with corticosteroids and immunosuppressants are crucial for managing this complex disorder.

Keywords:
AphthaeBehcetgiant

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Area of Science:

  • Oral Medicine
  • Immunology
  • Vascular Medicine

Context:

  • Aphthae are common oral ulcers with varied presentations.
  • Bipolar aphthae (oral and genital) are key indicators for systemic diseases.
  • Behçet's disease is a rare multisystem inflammatory disorder.

Purpose:

  • To highlight the diagnostic significance of recurrent aphthae, particularly bipolar aphthae, in identifying Behçet's disease.
  • To present a case study illustrating the link between oral aphthae, vascular issues, and uveitis.
  • To emphasize the importance of a comprehensive clinical evaluation for complex aphthosis.

Summary:

  • Aphthae, ranging from small ulcers to giant variants, can be triggered by foods or medications.
  • Complex or bipolar aphthosis may signal underlying conditions like celiac disease, nutritional deficiencies, or Behçet's disease.
  • A 40-year-old male with a femoral artery aneurysm, giant tongue aphthae, genital/buccal aphthae, and uveitis was diagnosed with Behçet's disease.

Impact:

  • This case underscores the necessity of considering systemic diseases in patients with recurrent or complex aphthae.
  • Prompt diagnosis and aggressive immunosuppressive therapy (corticosteroids, cyclophosphamide) are vital for managing Behçet's disease and preventing severe complications.
  • Highlights the multidisciplinary approach required for diagnosing and treating Behçet's disease, involving oral medicine, rheumatology, and ophthalmology.