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Topical and Oral Therapies for Childhood Atopic Dermatitis and Plaque Psoriasis

Travis Frantz1, Ellen G Wright1, Esther A Balogh1

  • 1Center for Dermatology Research, Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA.

Children (Basel, Switzerland)
|November 8, 2019
PubMed

Insights

Treating pediatric atopic dermatitis and psoriasis is challenging due to limited approved options. This review offers guidance on available topical and oral treatments, including off-label uses, for these conditions in children.

Area of Science:

  • Pediatric Dermatology
  • Dermatological Therapeutics

Background:

  • Pediatric atopic dermatitis and psoriasis management is hindered by a lack of standardized guidelines and FDA-approved treatments.
  • Adult treatments are often used off-label in pediatric populations.

Purpose of the Study:

  • To review available topical and oral treatment options for pediatric atopic dermatitis and psoriasis.
  • To provide a basic therapeutic guideline, including off-label considerations.

Main Methods:

  • A PubMed literature search was conducted.
  • Focused on topical and systemic treatments for pediatric psoriasis and atopic dermatitis.
  • Information gathered included age appropriateness, efficacy, dosing, contraindications, adverse events, and off-label usage.

Main Results:

  • Seven topical and five systemic treatments are commonly used for pediatric atopic dermatitis and psoriasis.
  • Data on age, efficacy, dosing, contraindications, and adverse events were compiled.

Conclusions:

  • Standardized guidelines for treatment selection, dosing, and long-term safety in pediatric patients are scarce.
  • Current pediatric treatment approaches rely heavily on clinical experience and expert recommendations due to limited official approvals.
Abstract

Keywords:
atopic dermatitischildrenpediatricspsoriasistreatment

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