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Pulpal repair after direct pulp capping with new bioceramic materials: A comparative histological study
Khaled Wagih Al-Saudi1, Sameh Mahmoud Nabih2, Ahmed Mustafa Farghaly3
1Operative Dentistry Department, Faculty of Oral and Dental Medicine, Misr University for Science and Technology, Cairo, Egypt.
The Saudi Dental Journal
|November 8, 2019
Summary
Direct pulp capping with TotalFill and Neo MTA Plus both promote favorable pulpal healing. TotalFill demonstrated a significantly thicker dentin bridge formation at three months compared to Neo MTA Plus.
Area of Science:
- Endodontics
- Dental Materials Science
- Regenerative Dentistry
Background:
- Direct pulp capping is a vital endodontic procedure to preserve pulp vitality.
- Bioceramic materials have shown promise in promoting pulpal healing.
- Evaluating novel materials like TotalFill and Neo MTA Plus is crucial for clinical application.
Purpose of the Study:
- To histopathologically assess pulpal healing following direct pulp capping.
- To compare the efficacy of TotalFill versus Neo MTA Plus in human tooth cultures.
- To evaluate dentin bridge formation and inflammatory response.
Main Methods:
- Human premolars underwent pulp exposure and capping with TotalFill or Neo MTA Plus.
- Teeth were cultured for three weeks and three months.
- Histopathological evaluation of pulpal healing and dentin bridge formation was performed.
Main Results:
- Both TotalFill and Neo MTA Plus resulted in complete dentin bridge formation.
- Absence of significant inflammatory pulp response was observed in both groups.
- TotalFill showed a significantly thicker dentin bridge at three months.
Conclusions:
- TotalFill and Neo MTA Plus exhibit comparable favorable pulpal healing and repair.
- TotalFill may promote thicker dentin bridge formation compared to Neo MTA Plus.
- These findings support the use of TotalFill in direct pulp capping procedures.

