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Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

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Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
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Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

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Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
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Related Experiment Video

Updated: Jan 4, 2026

MRI and PET in Mouse Models of Myocardial Infarction
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Stroke detection with 3 different PET tracers.

Ayca Dundar1, Michael S Bold1, Busranur Agac2

  • 1Department of Radiology, Mayo Clinic, 150 3rd Street SW, Rochester, MN 55905, USA.

Radiology Case Reports
|November 8, 2019
PubMed
Summary
This summary is machine-generated.

Positron emission tomography (PET) can incidentally detect stroke findings in oncology patients. Specific radiotracers show unique uptakes in ischemic or hemorrhagic stroke regions, suggesting PET

Keywords:
11C-Choline18F-FDG68Ga-DOTATATEPETStroke

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Area of Science:

  • Neurology
  • Nuclear Medicine
  • Radiology

Background:

  • Stroke is a leading cause of death and disability.
  • Positron emission tomography (PET) is widely used in oncology.
  • The utility of PET in stroke evaluation is under-explored.

Observation:

  • Incidental stroke findings were observed on oncologic PET/CT scans.
  • Utilized radiotracers included 18F-FDG, 11C-Choline, and 68Ga-DOTATATE.
  • Specific uptakes correlated with MRI-confirmed ischemic and hemorrhagic stroke.

Findings:

  • Focal 11C-Choline and 68Ga-DOTATATE uptake indicated ischemia.
  • Increased 18F-FDG activity surrounded hemorrhagic areas.
  • PET imaging revealed distinct patterns for different stroke types.

Implications:

  • PET imaging may offer novel insights into stroke pathophysiology.
  • PET could aid in evaluating stroke based on metabolic activity and receptor expression.
  • This highlights a potential secondary benefit of oncologic PET scans.