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Updated: Jan 4, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
Novel technique of performing multivessel PCI through an Impella sheath
Kris Kumar1, Sridhar Reddy1, Deepak Acharya1
1Sarver Heart Center, University of Arizona, Tucson, Arizona.
Insights
This case study demonstrates a novel approach for high-risk patients needing hemodynamic support. Percutaneous coronary intervention (PCI) was successfully performed via an Impella sheath, enabling simultaneous support and intervention.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Devices
Background:
- A 69-year-old female with diabetes presented with multi-vessel coronary artery disease requiring five-vessel coronary artery bypass grafting.
- Postoperatively, the patient experienced persistent cardiogenic shock, necessitating escalating vasopressor support and an intra-aortic balloon pump.
Observation:
- New ischemic changes on electrocardiogram prompted urgent cardiac catheterization for coronary angiography and Impella CP placement.
- Vascular access limitations led to the utilization of the Impella CP sheath for concurrent diagnostic angiography and percutaneous coronary intervention (PCI).
Findings:
- Successful diagnostic angiography and multi-vessel PCI, including stenting of a severe proximal obtuse marginal lesion, were performed through the Impella CP sheath.
- This represents the first reported instance of performing PCI via an Impella sheath while the device provided concurrent mechanical circulatory support.
Implications:
- This novel technique of using the Impella sheath for vascular access offers a potential strategy for high-risk patients with limited access sites.
- It may reduce bleeding complications by minimizing the number of arterial punctures required during complex cardiac procedures.
Abstract:
A 69-year-old woman with diabetes was found to have multi-vessel coronary artery disease and underwent 5-vessel coronary artery bypass grafting. Patient had persistent cardiogenic shock postoperatively despite intra-aortic balloon pump and escalating pressor requirements. Electrocardiogram showed new ischemic changes and the patient was urgently taken to the catheterization lab for coronary angiography and placement of an Impella CP for higher degree of hemodynamic support via the left femoral artery. Due to limitations in vascular access the Impella CP sheath was utilized for vascular access for diagnostic angiography and coronary intervention concurrently with ongoing Impella CP support. The first obtuse marginal had severe proximal disease and was treated with percutaneous coronary intervention (PCI) with a drug eluting stent. To our knowledge, this case is the first in which successful diagnostic angiography as well as multi-vessel PCI was performed via an Impella sheath while concurrently using the percutaneous mechanical circulatory support system of the Impella CP. Multiple guide catheters and a pigtail catheter were successfully passed via the Impella CP sheath to perform PCI. This novel method of vascular access could be an important tool to use in high-risk patients with limitations in access sites and decrease potential bleeding complications by limiting the number of arterial punctures.
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