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Osler-Weber-Rendu disease in an infant
M Reyes-Mújica1, E López-Corella, L Pérez-Fernández
1Department of Pathology, Instituto Nacional de Pediatría, DF, México.
Human Pathology
|October 1, 1988
Abstract:
A 23-month-old girl with Osler-Weber-Rendu (OWR) disease manifested by hemoptysis died of massive pulmonary hemorrhage. Autopsy showed predominant respiratory tract involvement, but telangiectatic vessels were also present in other sites. Skin lesions were absent. A grandfather had died after bleeding by mouth following physical exertion. This disease seldom appears in children and hemorrhage usually manifests after 30 years of age.