Localised granulomatosis with polyangiitis in an older patient with rheumatoid arthritis
Aina Capdevila-Reniu1, Sebastian De la Cruz Rodríguez-Garcia2, Ignacio Grafia1
1Geriatric Unit, Department of Internal Medicine, Hospital Clinic de Barcelona, Barcelona, Spain.
Abstract:
New onset of granulomatosis with polyangiitis (GPA) occurring in patients previously diagnosed with rheumatoid arthritis (RA) is very uncommon. In older individuals, this condition is associated with high mortality, especially in those with renal involvement. We describe the first case of GPA in a patient older than 65 years diagnosed with RA without exposure to biologic disease-modifying anti-rheumatic drugs, presenting with pulmonary nodules due to a limited form of anti-neutrophil cytoplasmic antibody-negative GPA.
Related Concept Videos
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption
Pharmacodynamics in Geriatric Patients: Effects of Age
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
Rheumatic Heart Disease I: Introduction
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism


