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Teeth01:15

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The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
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Author Spotlight: Insights into an Efficient Murine Maxillary Orthodontic Model Protocol
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Laser Photobiomodulation Over Teeth Subjected to Orthodontic Movement.

Joseli M Cordeiro1, Marcelo G Sahad1, Marcos F X B Cavalcanti2,3

  • 1Post Graduation Program in Orthodontics and Dentofacial Orthopedics, Cruzeiro do Sul University, São Paulo, Brazil.

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Summary

Low-level laser (LLL) therapy can accelerate orthodontic tooth movement by increasing interleukin (IL)-1, IL-10, and type 1 collagen levels. This study suggests LLL is a viable orthodontic movement acceleration protocol (OMAP).

Keywords:
IL-1IL-10collagen type 1low-level laser therapyphotobiomodulationtooth movement

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Area of Science:

  • Biomedical Engineering
  • Periodontology
  • Orthodontics

Background:

  • 21st-century orthodontics demands faster, aesthetic, and less painful treatments.
  • Orthodontic movement acceleration protocols (OMAPs) aim to expedite treatment outcomes.
  • Low-level laser (LLL) therapy is being investigated as a potential OMAP.

Purpose of the Study:

  • To assess the impact of LLL irradiation on interleukin (IL)-1, IL-10, and type 1 collagen levels in the periodontal ligament of rat molars during orthodontic traction.
  • To determine if the specific LLL dosage used qualifies as an OMAP.

Main Methods:

  • 35 male Wistar rats were divided into three groups: non-irradiated (NI), laser-irradiated (IR), and control (CO).
  • The IR group received LLL irradiation (5 J, 177 J/cm², 100 mW) applied to the gum tissue around the molar region for 3 consecutive days.
  • Groups NI and IR were subjected to orthodontic force, with subgroups sacrificed at 3, 5, and 7 days post-treatment for analysis of IL-1, IL-10, and COL-1 levels.

Main Results:

  • The laser-irradiated (IR) group demonstrated anticipated peak levels of IL-1, IL-10, and COL-1 compared to the non-irradiated (NI) and control (CO) groups.
  • These inflammatory and collagen markers indicate an accelerated biological response in the periodontal ligament following LLL treatment.

Conclusions:

  • The evaluated dose of low-level laser (LLL) shows potential as an effective orthodontic movement acceleration protocol (OMAP).
  • LLL irradiation can expedite biological processes in the periodontal ligament, supporting faster orthodontic tooth movement.