Attention-deficit hyperactivity disorder in adults with epilepsy
Nahid Ashjazadeh1, Ali Sahraeian2, Iman Sabzgolin3
1Shiraz Neuroscience Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Neurology, Shiraz University of Medical Sciences, Shiraz, Iran.
Epilepsy & Behavior : E&B
|November 8, 2019
Summary
Attention-deficit hyperactivity disorder (ADHD) is prevalent in adults with epilepsy (PWE). Routine screening for ADHD in PWE is recommended for early detection and management.
Area of Science:
- Neurology
- Psychiatry
Background:
- Epilepsy affects cognitive function and can co-occur with other neurological and psychiatric conditions.
- Attention-deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by inattention and/or hyperactivity-impulsivity.
Purpose of the Study:
- To investigate the prevalence of ADHD in adult people with epilepsy (PWE).
- To explore potential associations between clinical factors and ADHD in PWE.
Main Methods:
- A cross-sectional study involving 200 adult PWE recruited from a neurology clinic.
- Validated Persian versions of the Adult ADHD Self-Report Scale (ASRS v1.1) and Addenbrooke's Cognitive Examination-Revised (ACE-R) were administered.
- Univariate and logistic regression analyses were performed.
Main Results:
- 35% of the total PWE group screened positive for ADHD.
- A significant association was found between cognitive function and ADHD screening: 18% with normal cognition, 42% with mild impairment, and 70% with severe impairment screened positive (p=0.0001).
- In PWE with normal cognition only, 18% screened positive for ADHD, with no significant association with other tested variables.
Conclusions:
- Approximately one-fifth of adults with epilepsy and normal cognitive function may screen positive for ADHD.
- Routine screening for ADHD in all PWE is advisable for timely diagnosis and management.
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