Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Resetting of epigenetic cold memory through somatic embryogenesis in plant regeneration.

Nature plants·2026

Same author

Time-resolved reprogramming of single somatic cells into totipotent states during plant regeneration.

Cell·2025

Same author

Time-resolved reprogramming of single somatic cells into totipotent states during plant regeneration.

Cell·2025

Same author

LEC2 induces somatic cell reprogramming through epigenetic activation of plant cell totipotency regulators.

Nature communications·2025

Same author

A WRI1-dependent module is essential for the accumulation of auxin and lipid in somatic embryogenesis of Arabidopsis thaliana.

The New phytologist·2024

Same author

A Poisoning Case Involving Gymnopus dryophiloides (Agaricomycetes).

International journal of medicinal mushrooms·2024

Same journal

Modeling the impact of budget limitation on the screening and treatment pathway of HPV-induced precancerous cervical lesions.

Mathematical biosciences and engineering : MBE·2026

Same journal

Modeling the effects of trait-mediated dispersal on coexistence of two species: Competition and non-consumptive predator-prey.

Mathematical biosciences and engineering : MBE·2026

Same journal

A close look at the viral reduction rate in target cell limited models.

Mathematical biosciences and engineering : MBE·2026

Same journal

A stochastic agent-based model for simulating tumor-immune dynamics and evaluating therapeutic strategies.

Mathematical biosciences and engineering : MBE·2026

Same journal

Addressing domain shift via imbalance-aware domain adaptation in embryo development assessment.

Mathematical biosciences and engineering : MBE·2026

Same journal

Effect of drug resistance on an HIV epidemic in heterogeneous populations.

Mathematical biosciences and engineering : MBE·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jan 4, 2026

Assembly and Characterization of an External Driver for the Generation of Sub-Kilohertz Oscillatory Flow in Microchannels

Assembly and Characterization of an External Driver for the Generation of Sub-Kilohertz Oscillatory Flow in Microchannels

Published on: January 28, 2022

Quantitative generation of microfluidic flow by using optically driven microspheres.

Song Yu Hu¹, Rui Feng Hu², Li Ping Tang¹

¹College of Mechatronics and Control Engineering, Shenzhen University, Shenzhen 518060, China.

Mathematical Biosciences and Engineering : MBE

|November 9, 2019

Summary

This summary is machine-generated.

This study introduces a novel method for precise microfluidic flow generation using optically controlled microspheres. This technique offers accurate, localized fluid manipulation for biomedical applications.

Keywords:

microfluidic flow microfluidic system microsphere optical trap optical tweezers theoretical solution

More Related Videos

Generation of Size-controlled Poly ethylene Glycol Diacrylate Droplets via Semi-3-Dimensional Flow Focusing Microfluidic Devices

Generation of Size-controlled Poly ethylene Glycol Diacrylate Droplets via Semi-3-Dimensional Flow Focusing Microfluidic Devices

Published on: July 3, 2018

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices

Published on: September 2, 2009

Related Experiment Videos

Last Updated: Jan 4, 2026

Assembly and Characterization of an External Driver for the Generation of Sub-Kilohertz Oscillatory Flow in Microchannels

Assembly and Characterization of an External Driver for the Generation of Sub-Kilohertz Oscillatory Flow in Microchannels

Published on: January 28, 2022

Generation of Size-controlled Poly ethylene Glycol Diacrylate Droplets via Semi-3-Dimensional Flow Focusing Microfluidic Devices

Generation of Size-controlled Poly ethylene Glycol Diacrylate Droplets via Semi-3-Dimensional Flow Focusing Microfluidic Devices

Published on: July 3, 2018

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices

Published on: September 2, 2009

Area of Science:

Biophysics
Microfluidics
Optical Manipulation

Background:

Microfluidic flow generation is crucial for biological and medical applications.
Existing methods may lack precision or require specialized fabrication.

Purpose of the Study:

To develop a quantitative method for microfluidic flow generation using optical tweezers.
To achieve high precision and robustness in microfluidic control.

Main Methods:

Utilizing optical tweezers to move a microsphere automatically within a liquid.
Implementing a closed-loop control strategy with visual servoing feedback.
Deriving theoretical solutions based on Stokes equations for generated flow.

Main Results:

Demonstrated quantitative generation of microfluidic flow through controlled microsphere movement.
Achieved high precision and robustness via closed-loop visual feedback.
Validated the effectiveness of the proposed experimental method.

Conclusions:

Optically actuating liquids via microsphere translation with closed-loop control is a novel approach.
This method offers dexterous adjustment of microfluidic flow without dedicated microtool fabrication.
The technique is promising for precise, controllable localized microfluidics in biomedical applications.