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Mapping evidence on the distribution of paediatric cancers in sub-Saharan Africa: a scoping review protocol
Sehlisiwe R Ndlovu1, Desmond Kuupiel2, Themba G Ginindza2
1Discipline of Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa. sehlisiwen@gmail.com.
Insights
Childhood cancer distribution in sub-Saharan Africa (SSA) is poorly understood, leading to limited policy attention and access to care. This scoping review maps existing evidence to identify research gaps and improve paediatric cancer outcomes in SSA.
Area of Science:
- Oncology
- Public Health
- Epidemiology
Background:
- Paediatric cancers receive inadequate policy attention globally, particularly in low-income countries.
- Sub-Saharan Africa (SSA) faces underestimated childhood cancer burdens due to data limitations and weak healthcare systems.
- Lack of national paediatric cancer strategies hinders access to diagnosis and treatment for children in SSA.
Purpose of the Study:
- To map existing evidence on the distribution of paediatric cancers across the sub-Saharan Africa region.
- To identify research gaps concerning childhood cancer epidemiology in SSA.
- To inform policy and improve access to paediatric cancer care in SSA.
Main Methods:
- A comprehensive scoping review of published literature on paediatric cancers in SSA.
- Systematic electronic database searches (PubMed, Google Scholar, EBSCOhost, WHO/IARC GLOBOCAN) and reference list screening.
- Descriptive analysis of study characteristics and country-specific outcomes, presented narratively with tables, maps, and charts.
Main Results:
- The review will synthesize data on the geographical distribution of childhood cancers in SSA.
- It will highlight variations in reported paediatric cancer incidence and types across different countries.
- Key research gaps in data collection and epidemiological studies will be identified.
Conclusions:
- This study will provide a foundational overview of paediatric cancer distribution in SSA.
- Findings will guide future research priorities to address critical knowledge gaps.
- The results aim to support the development of targeted interventions and policies to improve childhood cancer care in the region.
Background:
Paediatric cancers account for a minor fraction of deaths and hence receive little attention from policymakers. In low-income countries, the absence of comprehensive national paediatric strategies results in a lack of access for a majority of children with cancer. In sub-Saharan Africa (SSA), the burden of childhood cancers is underestimated due to a lack of paediatric cancer registries, poor health care systems and competing healthcare needs. The objective of this study is to map evidence on the distribution of paediatric cancers in the SSA region.
Method:
A scoping review will be conducted to map literature on the distribution of paediatric cancers in SSA. An electronic literature search will be conducted from the following databases: PubMed, Google Scholar, EBSCOhost (CINAHL and Health Source) and World Health Organization (WHO)/International Agency for Research in Cancer (IARC) (GLOBOCAN databases). We will also search the reference lists of included studies to source relevant literature. A pilot search was conducted to determine the feasibility of the study. Study selection will be guided by the inclusion and exclusion criteria. After charting the data, a descriptive overview of the studies will be presented in a narrative format. An account of the study characteristics will be described in this narrative. The analysis will be mainly based on mapping the country-specific outcomes emerging from the studies, and a numerical summary of these outcomes will be conducted. Tables, maps and charts will be produced and presented in the result section.
Discussion:
This review study will identify existing research gaps for future research to influence policy implementation and to improve the availability of diagnosis and treatment of paediatric cancers in SSA.
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