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An Evidence-Based Guideline Supporting Restricted Opioid Prescription after Pediatric Appendectomy
Mollie R Freedman-Weiss1, Alexander S Chiu1, David Worhunsky1
1Yale University School of Medicine, New Haven, CT.
Insights
Most young patients undergoing laparoscopic appendectomy do not need opioids post-discharge. Prescribing sparingly, no more than 25 morphine milligram equivalents (MME), is recommended to curb opioid overprescription.
Area of Science:
- Pediatric Surgery
- Pain Management
- Public Health
Background:
- Surgeon overprescription of opioids contributes to the ongoing opioid epidemic.
- Lack of clear guidelines for pediatric and young adult post-surgical opioid prescribing exists.
Purpose of the Study:
- To determine postoperative opioid requirements in pediatric and young adult patients after laparoscopic appendectomy.
- To inform opioid prescribing guidelines for this demographic.
Main Methods:
- A study included patients aged 5-20 years who underwent laparoscopic appendectomy.
- Data collected via chart review and caregiver interviews on analgesic use and pain relief adequacy.
- Opioid consumption quantified in morphine milligram equivalents (MME).
Main Results:
- 83% of interviewed patients (49 total) did not use or desire opioids post-discharge and reported low pain levels (<4/10).
- Five patients used an average of 23 MME (approx. 3 pills of 5mg oxycodone).
- No patients who avoided opioids required unplanned follow-up for pain.
Conclusions:
- The majority of pediatric and young adult patients achieve adequate pain relief after laparoscopic appendectomy without opioids.
- Opioid prescriptions for this procedure should be limited, ideally not exceeding 25 MME.
Background/Purpose:
Surgeon overprescription of opioids is a modifiable contributor to the opioid epidemic. No clear guidelines exist for prescribing opioids to younger patients after surgery. We sought to determine postoperative opioid needs in pediatric/young adult patients after laparoscopic appendectomy.
Methods:
Patients 5-20 years old who underwent laparoscopic appendectomy were included for study. All consented patients underwent chart review and were additionally called for an attempted interview. Caregivers were queried on analgesic use and adequacy of pain relief. The main outcome measures were: quantity of opioid used, desire for an opioid, presence of pain ≥4/10, and need for follow-up/call owing to pain. All opioids were converted into morphine milligram equivalents (MME).
Results:
Seventy-three patients qualified for the study, 49 of whom completed a postoperative telephone interview. Of the interviewees, 83% did not use or desire an opioid and reported pain <4/10 after discharge. Five patients used an opioid upon discharge, and the average MME consumed was 23 (equivalent to 3 pills of 5 mg oxycodone). No zero-opioid patients had unanticipated follow-up for pain concerns.
Conclusions:
After hospital discharge following laparoscopic appendectomy, most patients have adequate analgesia without opioids. Opioid prescriptions should be offered sparingly and for no more than 25 MME.
Level Of Evidence:
Level II.
Type Of Study:
Prognosis study.
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