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Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
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Neurogenic bowel dysfunction.

Anton Emmanuel1

  • 1GI Physiology Unit, University College London Hospital, Euston Road, London, WC1E 6DB, UK.

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|November 9, 2019
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Summary
This summary is machine-generated.

Neurogenic bowel dysfunction (NBD) significantly impacts quality of life for patients with chronic neurological diseases. This review offers a stepwise approach to managing NBD symptoms, from conservative measures to surgical options.

Keywords:
Bowel DysfunctionConstipationFaecal incontinenceNeurogenic Bladder

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Area of Science:

  • Neurology
  • Gastroenterology

Background:

  • Neurogenic bowel dysfunction (NBD) presents with constipation and fecal incontinence, affecting the quality of life for individuals with chronic neurological conditions.
  • The majority of patients with multiple sclerosis, spinal cord injury, and Parkinson's disease experience these debilitating bowel symptoms.

Purpose of the Study:

  • To provide clinicians with practical, stepwise guidance for assessing and managing neurogenic bowel dysfunction.
  • To highlight objective measures for monitoring treatment response in NBD patients.

Main Methods:

  • Review of current literature and clinical practices for NBD management.
  • Emphasis on a structured, stepwise approach to interventions.

Main Results:

  • Conservative management, including diet optimization and laxative use, forms the initial step.
  • Transanal irrigation is an effective intervention for approximately half of patients unresponsive to conservative care, improving quality of life.
  • Surgical options are available for refractory cases.

Conclusions:

  • A systematic, stepwise approach is crucial for effective NBD management.
  • Early assessment and tailored interventions, including transanal irrigation, can significantly improve patient outcomes and quality of life.
  • Objective monitoring is essential for evaluating treatment efficacy in NBD.